Gene delivery from a DNA controlled-release stent in porcine coronary arteries

Article Abstract:

This report examines angioplasty, the surgical procedure for treating heart disease using expandable intra-arterial stent with controlled dosage of DNA from a drug delivery system. The procedure on pig coronary angioplasty was performed at the University of Pennsylvania Medical Center and Children's Hospital, both in Philadelphia, Pennsylvania.

Production management, Health Care and Social Assistance, Surgical Appliance and Supplies Manufacturing, Surgical Procedures, HEALTH SERVICES, Surgical appliances and supplies, Medical Instruments and Supplies, Genetic Engineering, Surgical and Medical Instrument Manufacturing, Cardiovascular Therapy Equip, Angioplasty Supplies, Surgery, Cardiovascular equipment, Angioplasty devices

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Gene delivery from a DNA controlled-release stent in porcine coronary arteries

Article Abstract:

Researchers believe that local gene delivery could be accomplished with the controlled release of DNA from a polymer coating on an expandable stent.

Cardiovascular Preparations, Cardiovascular agents

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Antigen-specific downregulation of T cells by doxorubicin delivered through a recombinant MHC II-peptide chimera

Article Abstract:

There is the growing need to develop methods for delivering drugs that can be potentially therapeutic for T-cell-mediated diseases increases. One possible drug delivery system is MHC-peptide complexes that are the sole antigen-specific ligands for the T-cell receptor.

Cellular Biology, Cytology

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