Optimization of humanized IgGs in glycoengineered Pichia pastoris

Article Abstract:

A study was conducted to demonstrate that human antibodies with specific human N-glycan could be produced in glycoengineered lines of the yeast Pichia pastoris and that generating specific glycoforms could optimize antibody-mediated effector functions. The glycoengineered Pichia pastoris provides a general platform for producing recombinant antibodies with human N-glycosylation.

Research, Analysis, Usage, Physiological aspects, Glycosylation, Monoclonal antibodies, Yeast fungi, Yeasts (Fungi), Time-of-flight mass spectrometry

---

Bioartificial organs and acceptable risk

Article Abstract:

Scientists, surgeons and medical researchers in the United States, Switzerland, Canada and Italy discuss risks societally acceptable in surgical transplants, based on demands for artificial organs, biological products, surgical procedure and hormonal deficiency of patients.

Italy, United States, Canada, Research and Development in the Physical, Engineering, and Life Sciences, Switzerland, Health Care and Social Assistance, Biological Product (except Diagnostic) Manufacturing, Genetic Engineering, Biological Products NEC, Surgical Transplants, Biological products, Transplantation

---

Similar abstracts:

• Abstracts: An estimation of consumer benefits from the public campaign to lower cereal prices. Jawboning cereal: the campaign to lower cereal prices
• Abstracts: Similarities and contradictions in the core logic of three strategy research streams. Strategy research: governance and competence perspectives
• Abstracts: Accrual accounting and equity valuation. Accounting treatment of inherent versus incentive uncertainties and the capital structure of the firm
• Abstracts: cobA, a red fluorescent transcriptional reporter for Escherichia coli, yeast, and mammalian cells. Prospects for the use of nuclear transfer in human transplantation

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.