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Chemicals, plastics and rubber industries

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Association between hydrophobically modified polyanions and negatively charged bovine serum albumin

Article Abstract:

Research was conducted to examine the association between hydrophobically modified polyanions (HMPA) and negatively charged bovine serum albumin (BSA) using light scattering, equilibrium dialysis and viscometry. Pronounced increases of the scattering depending on the hydrophobicity of the synthetic polymer revealed the formation of complexes. Results support the proposed mechanism of thickening, upon addition of protein, observed previously in semidilute solutions of HMPA.

Author: Tribet, C., Porcar, I., Bonnefont, P.A., Audebert, R.
Publisher: American Chemical Society
Publication Name: Journal of Physical Chemistry B
Subject: Chemicals, plastics and rubber industries
ISSN: 1520-6106
Year: 1998
Polymers, Anions

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Interfacial water structure controls protein conformation

Article Abstract:

A phenomenological theory of salt-induced Hofmeister phenomena, which is based on a relation between protein solubility in salt solutions and protein-water interfacial tension, is described. The results have supported the ability of the new formalism to account for the diverse manifestations of salt effects on protein conformation dynamics, and stability and to resolve the puzzle of chaotropes stabilizing certain proteins conformation.

Author: Ramsden, J.J., Der, A., Kelemen, L., Fabian, L., Taneva, S.G., Fodor, E., Pali, T., Cupane, A., Cacace, M.G.
Publisher: American Chemical Society
Publication Name: Journal of Physical Chemistry B
Subject: Chemicals, plastics and rubber industries
ISSN: 1520-6106
Year: 2007
Science & research, Observations, Conformational analysis, Solution (Chemistry), Solutions (Chemistry), Protein conformation

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Subjects list: Research, Proteins
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