Genetic approaches to polyketide antibiotics. 1

Article Abstract:

Polyketides are a notable class of natural products with a number of well-established successes in clinical and agricultural applications and the examples of this class are, the antibiotics like erythromycin, tylosin, rifamycin, and tetracyclines. The so-called modular Polyketides15-17 have led to the most fruitful genetic engineering route to structural variants of polyketides that are important therapeutic drugs.

Antibiotics, Genetic aspects, Polyketides

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Plant cyclopeptides

Article Abstract:

Systematic and structural classification of plant cyclopeptides, is proposed, based on their structural skeletons and distributions in plants. Inferences drawn after reviewing the progresses in the chemistry and biology of cyclopeptides in higher plants reveal, that not all cyclopeptides are gene products and that there might be preliminary metabolites derived after processing large precursor proteins in plants.

Peptides, Plant physiology, Plant proteins

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