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Ratiometric single-molecule studies of freely diffusing biomolecules

Article Abstract:

This review examines the behavior of freely diffusing biomolecules in solution at single-molecular level using ratiometric fluorescence resonance energy transfer and confocal microscopy techniques. Application of the methodology to investigate protein folding and polymer physics, as revealed by bursts of photons of florescent biomolecules, is discussed.

Author: Schultz, Peter G., Deniz, Ashok A., Laurence, Ted A., Dahan, Maxime, Chemla, Daniel, Weis, Shimon
Publisher: Annual Reviews, Inc.
Publication Name: Annual Review of Physical Chemistry
Subject: Chemistry
ISSN: 0066-426X
Year: 2001
Measurement, Fluorescence, Protein folding, Resonance ionization spectroscopy

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Light-emitting electrochemical processes

Article Abstract:

This review discusses spectroscopic probing of the molecular aspects of homogeneous and heterogeneous electron transfer in electrochemical processes emitting light. Application of electrochemical processes to the solution redox reactions, ion- and electron conducting polymer hybrids, and to insulating polymers and thin films are presented.

Author: Armstrong, Neal R., Wightman, R. Mark, Gross, Erin M.
Publisher: Annual Reviews, Inc.
Publication Name: Annual Review of Physical Chemistry
Subject: Chemistry
ISSN: 0066-426X
Year: 2001
Research, Usage, Electroluminescence, Light-emitting diodes, LEDs, Electrochemistry

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Electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry

Article Abstract:

This article discusses principles, recent advances, and methods in coupling electrospray technique with mass spectrometry. Application of this technique in the elemental, conformational, and mass analysis of proteins and in the analysis of complex mixtures is described.

Author: Hendrickson, Christopher L., Emmett, Mark R.
Publisher: Annual Reviews, Inc.
Publication Name: Annual Review of Physical Chemistry
Subject: Chemistry
ISSN: 0066-426X
Year: 1999
Proteins, Isotopes, Protein structure, Mass (Physics), Ion cyclotron resonance spectrometry, Fourier transform spectroscopy

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Subjects list: Methods, United States, Analysis, Polymers, Optical properties, Biomolecules
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