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Synthesis and pharmacology of galantamine

Article Abstract:

Galantamine is an alkaloid that has attracted the interest of both organic chemists and pharmacologists, in a collaborative effort aimed at designing, preparing, and evaluating novel biologically active compounds for Alzheimer's diease (AD) treatment. An apparently complex molecule like galantamine can be very efficiently prepared in a few steps, in racemic or enentiomerically pure form, by using two reaction protocols.

Author: Marco-Contelles, Jose, Carreiras, Maria do Carmo, Rodriguez, Carolina, Villarroya, Mercedes, Garcia, Antonio G.
Publisher: American Chemical Society
Publication Name: Chemical Reviews
Subject: Chemistry
ISSN: 0009-2665
Year: 2006
Pharmacology, Galanthamine

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Lamellarins and related pyrrole-derived alkaloids from marine organisms

Article Abstract:

The research work related to lamellarins and related pyrrole-derived alkaloids isolated from marine organisms which exhibit important biological activities are reported. The results would provide insight into the structure-activity relationship of lamellarin and their potential application for the treatment of numerous diseases.

Author: Hamann, Mark T., Hui Fan, Jiangnan Peng, Jin-Feng Hu
Publisher: American Chemical Society
Publication Name: Chemical Reviews
Subject: Chemistry
ISSN: 0009-2665
Year: 2008
Structure-activity relationships (Biochemistry), Marine fauna, Marine animals

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Subjects list: Research, Chemical properties, Alkaloids
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