Does food restriction retard aging by reducing metabolic rate?

Article Abstract:

Food restriction in mice decreased metabolic rate by limiting oxygen consumption without altering body weight. This decrease in oxygen utilization of cells purportedly increased the life span of mice. Oxygen consumption should be equated with metabolic mass and it was shown that obese mice have reduced metabolic efficiency. The genetic and metabolic effects of food restriction resulted from decreased cellular redox potential and tissue damage. Aging therefore could be correlated with alterations in activities of metabolic organs.

Metabolism, Starvation

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Introduction

Article Abstract:

The condition called sarcopenia refers to the weakening of muscle function and loss of muscle mass in aging individuals. Sarcopenia is often thought to be a cause of functional constraints which eventually result in death. Research on the matter has yet to produce indubitable results. This functional loss may have to be regarded with the same importance as more commonly discussed aging symptoms such as circulatory disorders and dementia.

Muscles

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