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A better way for a cancer cell to die

Article Abstract:

A study of the lethal effects of chemotherapy on cancer cells shows that, after the fatal blow, cancer cells take different routes to destruction, depending on the chemotherapeutic agent used. The experiments indicate that if a chemotherapeutic agent kills cancer cells in a way that renders them immunogenic, it has a therapeutic benefit over and above the cytotoxic action of the drug.

Author: Lake, Richard A., van der Most, Robbert G.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2006
Cancer cells, Disease/Disorder overview

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Rational design of cancer-drug combinations

Article Abstract:

The possibility of a new preclinical approach that could hasten the rational design of active and minimally toxic combinations of small-molecule cancer drugs is discussed.

Author: Ramaswamy, Sridhar
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2007
Drug therapy, Combination, Combination drug therapy, Drug overview

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Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma.

Article Abstract:

A research proved that overall survival improved with Temsirolimus than with Interferon Alfa in patients suffering from advanced renal-cell carcinoma.

Author: Motzer, Robert J., Lustgarten, Stephanie, Hudes, Gary, Carducci, Michael, Figlin, Robert, Kapoor, Anil, Staroslawska, Elzbieta, Sosman, Jeffrey, McDermott, David, Bodrogi, Istvan, Kovacevic, Zoran, Lesovoy, Vladimir, Schmidt-Wolf, Ingo G.H., Barbarash, Olga, Gokmen, Erhan, O'Toole, Timothy, Moore, Laurence
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2007
Drug therapy, Interferon alpha, Carcinoma, Renal cell, Renal cell carcinoma, Clinical report

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Subjects list: Health aspects, Research, Antineoplastic agents, Antimitotic agents
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