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A practical method to calibrate self-reported adherence to antiretroviral therapy

Article Abstract:

The methods to calibrate patients' self-reported adherence to match objectively measured adherence more closely for the purpose of developing a practical and more accurate self-reported adherence measure are investigated. The method efficiently identified survey items to improve self-reported adherence measurement and the calibrated measure more closely approximates objectively measured adherence and is more sensitive for detecting nonadherence.

Author: Hays, Ron D., Liu, Honghu, Wenger, Neil S., Kaplan, Andrew H., Haubrich, Richard, Miller, Loren G., Golin, Carol E., Wagner, Glenn, Hu, Wenhua, Kahn, Katherine
Publisher: Lippincott Williams & Wilkins, WK Health
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2006
Analysis, Patient compliance

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Minimizing resistance consequences after virologic failure on initial combination therapy

Article Abstract:

A study is conducted to identify first-line therapies based on the rate of virologic success (VS) and the preservation of future treatment options in antiretroviral therapy (ART)-naive subjects. Intra- and interstudy comparisons showed higher VS rates for nonnucleoside reverse transcriptase inhibitor and boosted PI provide the highest rates of VS in treatment-naive HIV-infected persons.

Author: Mauskopf, Josephine A., Bartlett, John A., Davis, E. Anne, Lanier, E. Randall, Buda. Jeffrey J., von Scheele, Birgitta, Elston, Robert, King, Martin S.
Publisher: Lippincott Williams & Wilkins, WK Health
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2006
HIV infection, HIV infections

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Repeated measures longitudinal analyses of HIV virologic response as a function of percent adherence, dose timing, genotypic sensitivity and other factors

Article Abstract:

A detailed adherence information is collected using multiple tools along with demographic, clinical, social-behavioral and virologic measure. In HIV-infected participants initiating highly active antiretroviral therapy (HAART), it is found that long-term suppression of viral load (VL) as associated with taking a higher proportion of prescribed doses and smaller errors in dose timing.

Author: Hays, Ron D., Wenger, Neil S., Kaplan, Andrew H., Miller, Loren G., Honghu Liu, Golin, Carol E., Tongtong Wu
Publisher: Lippincott Williams & Wilkins, WK Health
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2006

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Subjects list: Health aspects, Care and treatment, Patient outcomes, HIV patients, Highly active antiretroviral therapy, Viral research, Virus research
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