A randomized pilot trial of administration of granulocyte colony-stimulating factor to women before preterm delivery

Article Abstract:

Giving women in premature labor granulocyte colony-stimulating factor could improve their baby's outcome. Premature infants have immature immune systems and have a high risk of bacterial infection. Granulocyte colony-stimulating factor boosts the production of immune cells. Researchers randomly gave granulocyte colony-stimulating factor or a placebo to 26 women in premature labor. Bone marrow biopsies on the newborn infants showed that those in the granulocyte colony-stimulating factor group had stronger immune systems. The chemical caused no serious adverse effects in mother or child.

Health aspects, Care and treatment, Physiological aspects, Infants (Premature), Premature infants, Premature birth, Granulocyte colony-stimulating factor

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Acquired von Willebrand disease: Management of labor and delivery with intravenous dexamethasone, continuous factor concentrate, and immunoglobulin infusion

Article Abstract:

Acquired von Willebrand disease is a rare bleeding disorder that can lead to complete absence of clotting factor 8 and von Willebrand factor. The first case of a pregnant woman with acquired von Willebrand disease who underwent the described therapy during delivery is described.

United States, Case studies, Dexamethasone, Blood diseases, Hematologic diseases, Von Willebrand's disease

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