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Acute rejection is associated with antibodies to non-Gal antigens in baboons using gal-knockout pig kidneys

Article Abstract:

A study to show that acute rejection is associated with antibodies to non-Gal antigens in baboons using Gal-knockout pig kidneys is presented. The data suggests that antibodies to non-Gal antigens will present an additional barrier to transplantation of organs from alpha 1, 3-galactosyltransferase knockout (GalT-KO) pigs to humans.

Author: Garcia, Bertha, White, David J., Gang Chen, Hua Qian, Starzl, Thomas, Hongtao Sun, Ximo Wang, Yifan Dai, Yishai Wise, Jevnikar, Anthony, Wanyu Wang, Yuanqing Liu, Yuliang Xiong, Wall, William, Ying Xiang, Cooper, David K C., Copeman, Laura, Murase, Niroko, Robert Zhong, Weihua Liu
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2005
Antigens

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Human and porcine early kidney precursors as a new source for transplantation

Article Abstract:

Resarch demonstrates the feasibility of using undefferentiated or partially developed human and pig kidney precursor cells in transplantation and organogenesis procedures. Results reveal that mice transplanted with such cells differentiate into functional nephrons and miniature kidneys.

Author: Reisner, Yair, Dekel, Benjamin, Burakova, Tatyana, Arditti, Fabian D., Reich-Zeliger, Shlomit, Milstein, Oren, Aviel-Ronen, Sarit, Rechavi, Gideon, Friedman, Nir, Kaminski, Naftali, Passwell, Justen H.
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2003
Israel, Physiological aspects, Kidney transplantation, Organogenesis

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Prospects for Parkinson disease

Article Abstract:

This article examines Parkinson's disease research, focusing on a study using fetal tissue transplants in Parkinson's patients. The author argues that more controlled research and standardization is needed before the benefits of neural transplantation can be realized.

Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2001
Usage, Parkinson's disease, Parkinson disease, Fetal nerve tissue

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Subjects list: Research, United States, Transplantation of organs, tissues, etc., Organ transplantation, Xenotransplantation, Tissue transplantation, Transplantation
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