Advances in H1-antihistamines

Article Abstract:

The differences in the clinical pharmacology and the similarities in efficacy and safety of the H1-antihistamines are reviewed for elaborating its role in neurotransmission,rengland c inflammation, and immune modulation. It is concluded that most H1-antihistamines have similar efficacy in allergic rhinoconjunctivitis and chronic urticaria, however, there are clinically relevant differences in their pharmacologic characteristics and their safety profiles.

Antihistamine Preparations, Dosage and administration, Antihistamines, Clinical pharmacology

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The preventive polypill - Much promise, insufficient evidence

Article Abstract:

Poor adherence to multidrug regimens is a common difficulty in effective therapy, but some observers believe this problem can be overcome through the 'polypill', which is a single pill that would include several key drugs. Although the concept of the polypill shows much promise, more clinical trials need to be conducted to provide evidence on the cost-effectiveness, safety, and adherence profile of the combination pill.

Cardiovascular Preparations, Cardiovascular agents, Drug overview

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Hepatocellular Carcinoma and sex

Article Abstract:

The article discusses a mouse based research that revealed estrogen countered pathway that provides insight into difference in prevalence of hepatocellular carcinoma between the sexes is reported.

Estrogen & Progestogen Preps, Genetic aspects, Estrogen, Estrogens, Interleukin-6, Sex research, Hepatoma, Hepatocellular carcinoma

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