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Age-Related Alterations in Sleep Quality and Neuroendocrine Function: Interrelationships and Implications

Article Abstract:

Age-related changes in sleep may affect hormone levels, which in turn may cause changes in body composition and function. A study published in 2000 showed that a decrease in deep sleep in older men caused a decrease in growth hormone levels. Growth hormone is secreted at night, usually during deep sleep.

Author: Blackman, Marc R.
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2000
Editorial

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Basal Muscle Amino Acid Kinetics and Protein Synthesis in Healthy Young and Older Men

Article Abstract:

The loss of muscle tissue in aged people is not caused by changes in protein and amino acid metabolism, according to a study of 26 young men and 22 elderly men. It is likely that a combination of factors causes muscle loss, which in turn leads to loss of strength, function, and independence.

Author: Wolfe, Robert R., Volpi, Elena, Sheffield-Moore, Melinda, Rasmussen, Blake B.
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2001
Muscles, Proteins, Protein synthesis, Amino acid metabolism

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Age-Related Changes in Slow Wave Sleep and REM Sleep and Relationship With Growth Hormone and Cortisol Levels in Healthy Men

Article Abstract:

Changes in sleep stages in old age appear to alter blood levels of some hormones. In a study of 149 men, older men with fewer deep sleep stages had lower levels of growth hormone. However, a decrease in REM sleep after the age of 50 caused increased levels of cortisol.

Author: Cauter, Eve Van, Leproult, Rachel, Plat, Laurence
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2000
Hydrocortisone

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Subjects list: Aging, Physiological aspects, Somatotropin, Sleep, Sleep stages
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