Angiotensinogen Thr235 variant is associated with abnormal physiologic change of the uterine spiral arteries in first-trimester decidua

Article Abstract:

Pregnant women with a gene mutation called the angiotensinogen Thr235 variant may have a greater risk of developing preeclampsia. Preeclampsia is a complication of pregnancy characterized by hypertension and abnormal blood clotting. Researchers examined the spiral arteries of the uterus in endometrial samples from 53 women who had a first trimester abortion. The arteries were abnormal in the 11 women with the angiotensinogen Thr235 gene variation but not in the women who had the normal version of the gene. Abnormal changes in these arteries could lead to the physiologic changes seen in preeclampsia.

Abnormalities, Genetic aspects, Blood vessels, Preeclampsia, Uterus, Uterine circulation

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Endoscopic coverage of fetal myelomeningocele in utero

Article Abstract:

It may be possible to surgically repair a fetal myelomeningocele before the baby is born. Fetal myelomeningocele is a severe type of spina bifida in which the baby's spinal cord protrudes through the skin because of a defect in the spine. Researchers tried to correct the defect in four fetuses using laparoscopic surgery. The surgery was successful but two babies died from other causes. The two remaining babies were born and are healthy. Researchers believe exposure to amniotic fluid may damage the spinal cord in these cases. Thus, prenatal surgery may be the best treatment for these infants.

Innovations, Surgery, Prenatal care, Fetal surgery, Myelomeningocele, Meningomyelocele

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Defecation in utero: a physiologic fetal function

Article Abstract:

Doctors provide evidence that the fetus does have bowel movements, contrary to what many doctors believe. They did this by using ultrasound to visualize the anal region of the fetus, using the tissue harmonic imaging mode of the ultrasound system. This allows more detailed imaging of the anal region and any fecal material that is eliminated.

Defecation

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