Antigen-independent determinants of cadaveric kidney transplant failure

Article Abstract:

There are several reasons why a kidney transplant can fail independently of an antigen mismatch. Researchers followed 31,515 people who received a kidney transplant for five years. During the study, 5,883 patients had to begin dialysis because their transplant failed, 2,404 died with a failed transplant and 2,041 died with a functioning kidney. Young patients were more likely to have a graft failure, as were those with large body surface area. The age of the donor also contributed, with donors between 15 and 34 offering the best chance of a functioning graft.

Risk factors, Graft rejection, Kidneys, Kidney transplantation

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Update: Creutzfeldt-Jakob disease associated with cadaveric dura mater grafts--Japan, 1979-2003

Article Abstract:

Ninety-seven Japanese patients who received the LYODURA dura mater graft manufactured by B. Braun Melsungen AG, Germany, between 1978 and 1991 have developed Creutzfeldt-Jakob disease (CJD). CJD is a human brain disease similar to mad cow disease. The dura mater grafts were made from brain tissue taken from human cadavers. It may take over 20 years for CJD to develop in patients who received this graft.

Product standards, safety, & recalls, Germany, Product defects and recalls, Causes of, Medical equipment and supplies industry, Medical equipment industry, Contamination, Creutzfeldt-Jakob disease, Brain tissue transplantation, B. Braun Melsungen AG, Dura mater

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The Consent Process for Cadaveric Organ Procurement: How Does It Work? How Can It Be Improved?

Article Abstract:

Organ procurement organizations in the US vary in the consent procedure they follow. In a survey of 61 organ procurement organizations, some follow the deceased patient's wishes and some follow the family's wishes. Durable power of attorney had more weight among these organizations than living wills or donor cards.

Research, Informed consent (Medical law), Informed consent, Donation of organs, tissues, etc., Tissue donation

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