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Association of FKBP5 polymorphisms and childhood abuse with risk of posttraumatic stress disorder symptoms in adults.

Article Abstract:

A study to ascertain the relationship betweenchildhood abuseand the risk of developing stress disorder symptoms in adults was conducted. Results did not find any significant relation but suggested a potential gene-childhood environment that could cause adult posttraumatic stress disorder.

Author: Nemeroff, Charles B., Wei Liu, Ressler, Kerry J., Cubells, Joseph F., Epstein, Michael P., Binder, Elisabeth B., Bradley, Rebekah G., Rebekah G., Deveau, Todd C., Mercer, Kristina B., Yilang Tang, Gillespie, Charles F., Heim, Christine M., Schwartz, Ann C.
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2008
United States, Science & research, Other Justice, Public Order, and Safety Activities, Child Abuse, Psychological aspects, Health aspects, Research, Genetic aspects, Post-traumatic stress disorder, Single nucleotide polymorphisms, Clinical report

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Pituitary-Adrenal and Autonomic Responses to Stress in Women After Sexual and Physical Abuse in Childhood

Article Abstract:

Women who were abused as children have greater physiological responses to stress, according to a study of 49 women. The women who were abused as children and currently were depressed had the highest levels of pituitary and adrenal hormones that are produced during stress.

Author: Nemeroff, Charles B., Heim, Christine, Newport, D. Jeffrey, Heit, Stacey, Graham, Yolanda P., Wilcox, Molly, Bonsall, Robert, Miller, Andrew H.
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2000
Physiological aspects, Stress (Physiology), Adult child abuse victims

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Paroxetine for the prevention of depression induced by high-dose interferon alfa

Article Abstract:

Pretreatment with the antidepressant drug Paxil can reduce the risk of depression in cancer patients who take interferon alfa-2b. Depression is a known side effect of interferon alfa-2b treatment.

Author: Nemeroff, Charles B., Miller, Andrew H., Musselman, Dominique L., Lawson, David H., Gumnick, Jane F., Manatunga, Amita K., Penna, Suzanne, Goodkin, Rebecca S., Greiner, Kristen
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2001
Evaluation, Product/Service Evaluation, Prevention, Complications and side effects, Depression, Mental, Depression (Mood disorder), Interferon alpha, Paroxetine, Paxil (Medication)

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