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Biochemical Outcome Following External Beam Radiation Therapy With or Without Androgen Suppression Therapy for Clinically Localized Prostate Cancer

Article Abstract:

Men with moderate to advanced prostate cancer may benefit from radiation therapy plus androgen suppression therapy, according to a study of 1,586 men. Hormones often stimulate cancer growth, so drugs are used to suppress hormone production.

Author: Kantoff, Philip W., D'Amico, Anthony V., Schultz, Delray, Loffredo, Marian, Dugal, Raymond, Hurwitz, Mark, Kaplan, Irving, Beard, Clair J., Renshaw, Andrew A.
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2000

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Androgen suppression and radiation vs radiation alone for prostate cancer

Article Abstract:

A comparative study of the androgen suppression therapy (AST) and radiation therapy (RT) used for the treatment of prostate cancer is presented. The results show that AST leads to an increase in the overall survival in men with cancer.

Author: Kantoff, Philip W., D'Amico, Anthony V., Loffredo, Marian, Renshaw, Andrew A., Ming-Hui Chen
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2008
United States, Complications and side effects, Dosage and administration, Chemotherapy, Combination, Combination chemotherapy, Antiandrogens, Clinical report

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Biochemical Outcome After Radical Prostatectomy, External Beam Radiation Therapy, or Interstitial Radiation Therapy for Clinically Localized Prostate Cancer

Article Abstract:

Interstitial radiation (implant) therapy may be as effective as other prostate cancer treatments in men with mild disease but not in men with more severe disease. The radioactive implants can be used to treat a tumor that has not metastasized. Researchers compared implant therapy with radical prostatectomy (RP) or external beam radiation (RT) in 1,872 men with prostate cancer. All three treatments produced similar outcomes in men with mild disease but RP and RT provided better outcomes than radioactive implants in men with more severe disease.

Author: D'Amico, Anthony V., Schultz, Delray, Renshaw, Andrew A., Whittington, Richard, Tomaszewski, John E., Malkowicz, S. Bruce, Blank, Kenneth, Broderick, Gregory A.
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1998
Prostatectomy, Radioisotope brachytherapy, Brachytherapy

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Subjects list: Care and treatment, Evaluation, Prostate cancer, Radiotherapy
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