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Blood pressure and the risk of cardiovascular disease

Article Abstract:

People who don't have hypertension may still have a high risk of cardiovascular disease, especially if they have other risk factors. Studies have shown that the risk of death from cardiovascular disease continuously rises as blood pressure rises. Therefore, even people with blood pressure that is slightly higher than normal may benefit from lowering blood pressure. Since there are many more people in this category than there are people with hypertension, the use of antihypertensive drugs in this group would have a much larger impact on public health.

Author: MacMahon, Stephen
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2000
Editorial, Hypertension, Cardiovascular diseases

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Pravastatin therapy and the risk of stroke

Article Abstract:

Pravastatin may reduce the risk of stroke in patients with elevated cholesterol levels. Some studies have found that elevated cholesterol levels are a risk factor for stroke. Pravastatin is a drug that lowers blood cholesterol levels. In a study of 9,014 patients with a history of heart attack or angina, those who were taking pravastatin had a slightly lower risk of stroke than those taking a placebo, or inactive substance.

Author: MacMahon, Stephen, White, Harvey D., Simes, R. John, Anderson, Neil E., Hankey, Graeme J., Watson, John D.G., Hunt, David, Colquhoun, David M., Glasziou, Paul, Kirby, Adrienne C., West, Malcolm J., Tonkin, Andrew M.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2000
Evaluation, Prevention, Stroke (Disease), Stroke, Hypercholesterolemia, Pravastatin

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Relation between renal dysfunction and cardiovascular outcomes after myocardial infraction

Article Abstract:

Renal failure is associated with one of the highest risks, but the influence of milder degrees of renal impairment is less well defined. Even mild renal disease, as assessed by the estimated glomerular filtration rate (GFR), should be considered a major risk factor for cardiovascular complications after a myocardial infraction.

Author: White, Harvey D., Solomon, Scott D., Pfeffer, Marc A., McMurray, John J.V., Velazquez, Eric J., Kober, Lars, Zelenkofske, Steven, Anavekar, Nagesh S., Rouleau, Jean-Lucian, Nordlander, Rolf, Maggioni, Aldo, Dickstein, Kenneth, Leimberger, Jeffery D., Callif, Robert M.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2004
Causes of, Complications and side effects, Heart attack, Glomerular filtration rate, Kidney failure

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Subjects list: Health aspects, Risk factors
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