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Nonsustained ventricular tachycardia in coronary artery disease: relation to inducible sustained ventricular tachycardia

Article Abstract:

The electrocardiogram characteristics of patients with spontaneous episodes of extremely rapid heartbeat may not be useful in determining which patients will show sustained rapid heartbeat in response to electrical stimulation. Both spontaneous episodes and induced episodes of rapid heartbeat have been shown to predict sudden death. Researchers attempted to stimulate rapid heartbeat in 1,480 patients with coronary artery disease and spontaneous episodes of ventricular tachycardia. None of the characteristics of the patient's electrocardiogram proved useful in determining which patients were likely to respond to the stimulation.

Author: Talajic, Mario, Buxton, Alfred E., Lee, Kerry L., DiCarlo, Lorenzo, Greer, G. Stephen, Prystowsky, Eric N., Fisher, John D., Echt, Debra S., Josephson, Mark E., Packer, Douglas
Publisher: American College of Physicians
Publication Name: Annals of Internal Medicine
Subject: Health
ISSN: 0003-4819
Year: 1996
Analysis, Physiological aspects, Electrocardiogram, Electrocardiography, Ventricular tachycardia

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Electrophysiologic testing to identify patients with coronary artery disease who are at risk for sudden death

Article Abstract:

Patients with coronary artery disease (CAD) whose hearts can be stimulated to produce an arrhythmia have a higher risk of sudden death than other CAD patients. The heart is stimulated by a procedure called electrophysiology and the resulting arrhythmia is called an inducible arrhythmia. Researchers compared mortality rates in 353 CAD patients who had an inducible arrhythmia and 1,397 CAD patients who did not have an inducible arrhythmia. After 5 years, 32% of those with an inducible arrhythmia had died from cardiac arrest, compared to 24% of those without an inducible arrhythmia.

Author: Talajic, Mario, Buxton, Alfred E., Lee, Kerry L., DiCarlo, Lorenzo, Gold, Michael R., Greer, G. Stephen, Prystowsky, Eric N., O'Toole, Michael F., Tang, Anthony, Fisher, John D., Coromilas, James, Hafley, Gail
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2000
Patient outcomes, Mortality, Risk factors, Coronary heart disease, Cardiac arrest, Electrophysiology

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Prevention of implantable-defibrillator shocks by treatment with sotalol

Article Abstract:

The beta blocker sotalol may reduce the risk of inappropriate shocks in patients who have an implantable defibrillator. Implantable defibrillators are used to deliver a shock to the heart when it begins to beat too fast. However, some shocks can be inappropriate. In a study of 352 patients with an implantable defibrillator who began taking sotalol or a placebo, sotalol lowered the risk of an inappropriate shock by 64%. It also reduced the risk of death or shock from any cause, whether appropriate or not.

Author: Prystowsky, Eric N., Henry, Philip D., Hohnloser, Stefan H., Pacifico, Antonio, Saksena, Sanjeev, Williams, John H., Tao, Ben
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1999
Health aspects, Evaluation, Prevention, Cardiovascular instruments, Implanted, Cardiovascular implants, Electric countershock, Sotalol

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