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Noninvasive Imaging for the Diagnosis of Coronary Artery Disease: Focusing the Development of New Diagnostic Technology

Article Abstract:

New non-invasive diagnostic technologies must be relatively inexpensive and have excellent sensitivity and specificity to be cost-effective compared to other techniques used t0 diagnose coronary artery disease. New tests, such as MRI, electron-beam CT, exercise echocardiography, exercise single-photon emission CT, and coronary angiographymagnetic resonance imaging (MRI) and electron-beam computed tomography (CT), were tried. At a cost of $75,000 per added life-year, a test that costs $1000 would need a sensitivity of 94% and a specificity of 90% to be cost-effective. At $50 000 per year gained, a test for $500 must have both sensitivity and specificity of 95%.

Author: Kuntz, Karen M., Brady, Thomas J., Hunink, Maria G.M., Fleischmann, Kirsten E.
Publisher: American College of Physicians
Publication Name: Annals of Internal Medicine
Subject: Health
ISSN: 0003-4819
Year: 1999
Statistics, CT imaging, CAT scans, Magnetic resonance imaging, Cost benefit analysis, Angiocardiography

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Cost-Effectiveness of Diagnostic Strategies for Patients with Chest Pain

Article Abstract:

It may be unnecessary to use invasive diagnostic tests such as coronary angiography in patients with chest pain who have risk factors for coronary artery disease. Based on a review of the literature, researchers estimated that coronary angiography was only cost-effective in people with risk factors for coronary artery disease. However, in those with no risk factors, exercise echocardiography was more cost-effective. This is a non-invasive technique that uses ultrasound to monitor heart function while the patient walks on a treadmill or rides an exercise bike.

Author: Kuntz, Karen M., Douglas, Pamela S., Hunink, Maria G.M., Fleischmann, Kirsten E.
Publisher: American College of Physicians
Publication Name: Annals of Internal Medicine
Subject: Health
ISSN: 0003-4819
Year: 1999
Chest pain

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Exercise Echocardiography or Exercise SPECT Imaging?

Article Abstract:

Exercise echocardiography (ECHO) appears to be slightly better than exercise single-photon emission computed tomography (SPECT) imaging in diagnosingof coronary artery disease. An analysis of 44 studies that compared these two diagnostic imaging techniques found that both techniques accurately identified most of the patients with coronary artery disease but exercise ECHO was better at ruling out the disease in people who did not have it. Both techniques were better than traditional exercise testing.

Author: Kuntz, Karen M., Douglas, Pamela S., Fleischmann, Kirsten E., M. Hunink, Maria G.
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1998
SPECT imaging, Single photon emission computed tomography

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Subjects list: Evaluation, Economic aspects, Diagnosis, Coronary heart disease, Echocardiography, Diagnosis, Noninvasive, Noninvasive diagnosis
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