Calcitonin gene-related peptide receptor antagonist BIBN 4096 BS for the acute treatment of migraine

Article Abstract:

An international, randomized clinical trial was conducted to examine the effect BIBN 4096 BS on 126 patients with migraine after they received it intravenously over a period of ten minutes. The results showed that the Calcitonin gene-related peptide (CGRP) antagonist BIBN 4096 BS was effective in treating acute attacks of migraine.

United States, Usage, Clinical trials, Peptides, Migraine

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NXY-059 for acute ischemic stroke

Article Abstract:

NXY-059, a free-radical-trapping agent that is neuroprotective in animal models of stroke is tested on humans to see if it would reduce disability after acute ischemic stroke. The results show a benefit in terms of the prespecified primary end point, a reduction in disability as measured by the modified Rankin score at 90 days.

New England States, Health aspects, New England, Placebos

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NXY-059 for the treatment of acute ischemic stroke

Article Abstract:

The efficacy of the free-radical-trapping agent NXY-059 as a neuroprotectant is assessed in the Stroke-Acute Ischemic NXY Treatment II (SAINT II) trial. The results have shown that NXY-059 is safe but ineffective for the treatment of acute ischemic stroke within 6 hours after the onset of symptoms.

Diagnosis, Clinical report, Disease/Disorder overview

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