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Cancer vaccine strategies get bigger and better

Article Abstract:

A properly designed cancer vaccine can be very effective, as shown by a study of 20 lymphoma patients who were given granulocyte-macrophage colony stimulating factor in addition to the cancer vaccine. GM-CSF promotes the presentation of the tumor antigen to cytotoxic T cells.

Author: Curiel, David T., Gruijl, Tanja D. de
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 1999

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Prime boost vaccines power up in people

Article Abstract:

Vaccines that use DNA for priming and recombinant modified vaccinia Ankara virus (MVA) for boosting show great promise in pre-clinical models. This heterologous prime-boost protocol that is used in human trials is discussed.

Author: Robinson, Harriet L.
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2003
Clinical trials, Vaccines

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A new genetic method to generate and isolate small, short-lived but highly potent dendritic cell-tumor cell hybrid vaccines

Article Abstract:

For the preparation of cancer vaccines, fusion of tumor cells with antigen-presenting cells has been used. Characterization of cell fusion, which helps in identification, is discussed.

Author: Bateman, Andrew, Vy phan, Errington, Fiona, Chiat Cheong, Kottke, Tim, Grough, Michael, Altmann, Sharon, Bradenburger, Annick, Emery, Steve, Strome, Scott, Bonnette, Bernard, Melcher, Alan, Vile, Richard
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2003
Product development, Analysis, Usage, Cell interaction, Cell interactions, Tumors, Plant, Plant tumours, Plant tumors

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Subjects list: Research, Cancer vaccines
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