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Case 23-2005: A 57-year-old man with a mass in the liver

Article Abstract:

A 57-year-old man was admitted to the hospital because of a mass, that was 4 cm in diameter, in the dome of the right lobe of the liver, which was identified with the help of computed tomographic (CT) scanning and magnetic resonance imaging (MRI) of the abdominal area. Liver transplantation was considered as the primary treatment because it has the benefits of simultaneous removal of the primary cancer and replacement of the underlying cirrhotic liver, from which subsequent cancers may rise.

Author: Chung, Raymond T., Lauwers, Gregory Y., Blaszkowsky, Lawrence S., Tanabe, Kenneth K., Blake, Michael A.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2005
United Kingdom, Usage, Diagnosis, Liver, Liver transplantation, Magnetic resonance imaging

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Epidermal growth factor gene functional polymorphism and the risk of hepatocellular carcinoma in patients with cirrhosis

Article Abstract:

A study was undertaken to examine the relation among human epidermal growth factor gene and the risk of hepatocellular carcinoma. Results revealed that the incidence of developing hepatocellular carcinoma was higher in patients who suffered from liver cirrhosis and carried the epidermal growth factor gene.

Author: Chung, Raymond T., Lanuti, Michael, Finkelstein, Dianne M., Lauwers, Gregory Y., Tanabe, Kenneth K., Lemoine, Antoinette, Kawasaki, Hiroshi, Fujii, Tsutomu, Kulu, Yakup, Muzikansky, Alona, Kuruppu, Darshini, Goodwin, Jonathan M., Azoulay, Daniel, Fuchs, Bryan C.
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2008
United States, Science & research, Research, Risk factors, Epidermal growth factor, Epidermal growth factors, Hepatoma, Hepatocellular carcinoma, Clinical report

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Case 33-2006: A 43-year-old man with diabetes, hypogonadism, cirrhosis, arthralgias and fatigue

Article Abstract:

A 43-year-old man is diagnosed with hereditary hemochromatosis due to a mutation in the HFE gene with diabetes, hypogonadotropic hypogonadism, and probable hepatic cirrhosis. It is found that this case is consistent with HFE-related hereditary hemochromatosis with severe iron overload.

Author: Misdraji, Joseph, Chung, Raymond T., Sahani, Dushyant V.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2006
Diabetes, Diabetes mellitus, Hemochromatosis, Case study

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Subjects list: Case studies, Liver cirrhosis, Genetic aspects
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