Clinical equivalence of intranasal and oral 17beta-estradiol for postmenopausal symptoms

Article Abstract:

Giving women estrogen replacement therapy via a nasal spray can be beneficial and can avoid the problems with oral and transdermal delivery. This was the conclusion of a study of 659 postmenopausal women who took oral or intranasal estrogen or a placebo for 24 weeks.

Care and treatment, Hormone therapy, Menopause

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Low doses of estradiol in combination with gestodene to prevent early postmenopausal bone loss

Article Abstract:

A 1 milligram dose of estradiol is sufficient to maintain bone density in postmenopausal women, according to a study of 278 women. Estradiol in high doses may increase the risk of cancer. Women with few symptoms of menopause may benefit from lower doses.

Prevention, Osteoporosis, Estradiol

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Progestational effects of combinations of gestodene on the postmenopausal endometrium during hormone replacement therapy

Article Abstract:

Lower doses of gestodene appear to reduce the risk of uterine bleeding. Gestodene is a synthetic version of progesterone that is used in hormone replacement therapy.

Physiological aspects, Endometrium, Progestational hormones

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