Clinical versus statistical significance as they relate to the efficacy of periodontal therapy

Article Abstract:

Dentists must establish a set of criteria to determine whether any particular treatment for periodontal disease results in a clinical benefit for the patient. Many research studies only evaluate whether one particular treatment is statistically better than another treatment. However, statistical significance is not the same as clinical significance. A treatment can be statistically better than no treatment at all but still not provide a substantial clinical benefit to the patient.

Statistical hypothesis testing, Statistical significance

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Efficacy of subantimicrobial dosing with doxycycline: point/counterpoint

Article Abstract:

Low doses of the antibiotic doxycycline may be beneficial for patients with periodontal disease. The effect is very small but long-term use of low doses did not cause drug resistance on the part of the bacteria.

Health aspects, Drug therapy, Doxycycline

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Nonsurgical periodontal therapy in 2000: a literature review

Article Abstract:

Most patients with mild-to-moderate periodontal disease can be treated with manual and ultrasonic cleaning. Antibiotics can be used for patients who do not respond to this treatment.

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