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Comparison of primary coronary angioplasty and intravenous thrombolytic therapy for acute myocardial infarction: a quantitative review

Article Abstract:

Coronary angioplasty may be more effective than thrombolytic drugs in treating patients with a heart attack. These techniques are both used to open clogged arteries and dissolve blood clots that cause most heart attacks. Researchers evaluated 10 randomized clinical trials that compared angioplasty with several types of thrombolytic therapy. Overall 30-day mortality was 4% in the 1,290 patients treated with angioplasty and 6% in the 1,316 patients who received thrombolytic therapy. Angioplasty reduced the rate of recurrent heart attack or death by almost half and also reduced the risk of stroke.

Author: Weaver, W. Douglas, Simes, R. John, Grines, Cindy L., Gibbons, Raymond J., Zijlstra, Felix, Betriu, Amadeo, Garcia, Eulogio, Grinfeld, Lilliana, Ribeiro, Expedito E., DeWood, Marcus A., Ribichini, Flavio
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1997
Thrombolytic therapy

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Mortality benefit of immediate revascularization of acute ST-segment elevation myocardial infarction in patients with contraindications to thrombolytic therapy: a propensity analysis

Article Abstract:

People admitted to a hospital with heart attack symptoms who cannot take thrombolytic drugs should have immediate coronary angioplasty or coronary bypass surgery, according to a study of 19,917 patients. The patients who had either of these two operations had a 50% lower mortality rate on average while they were hospitalized than patients who did not. Thrombolytic drugs, angioplasty, and bypass surgery are all used to open blocked coronary arteries and restore blood flow to the heart.

Author: Parsons, Lori, Zalenski, Robert J., Grzybowski, Mary, Clements, Elizabeth A., Welch, Robert, Tintinalli, Anne T., Ross, Michael A.
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2003
Coronary artery bypass

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Prognostic Value of a Normal or Nonspecific Initial Electrocardiogram in Acute Myocardial Infarction

Article Abstract:

Patients with chest pain who have a normal electrocardiogram have a lower risk of dying from a heart attack than patients with an abnormal electrocardiogram. However, the mortality rate in the patients with a normal electrocardiogram was still about 6% compared to a 12% mortality rate in those with an abnormal electrocardiogram.

Author: Every, Nathan R., Malmgren, Judith A., Frederick, Paul D., Welch, Robert D., Zalenski, Robert J., Compton, Scott, Grzybowski, Mary, Thomas, Sophia, Kowalenko, Terry
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2001
Prognosis, Electrocardiography

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Subjects list: Care and treatment, Evaluation, Heart attack, Transluminal angioplasty, Balloon angioplasty
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