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Short-course antimicrobial treatment for acute otitis media: not best for infants and young children

Article Abstract:

Children younger than six years old who have otitis media should be treated with antibiotics for at least 10 days. Otitis media is a middle ear infection. Widespread antibiotic use has been linked to the rise of drug-resistant bacteria and otitis media accounted for 90% of all antibiotic use in young children in 1997. Consequently, some physicians recommend a shorter treatment course of no more than five days compared to the usual 10 to 14 days. However, several studies have shown that children younger than two years often do not benefit from short-course antibiotic treatment.

Author: Paradise, Jack L.
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1997
Antibiotics, Drug therapy, Dosage and administration

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The Heritability of Otitis Media: A Twin and Triplet Study

Article Abstract:

There appears to be a strong genetic component to otitis media, which is an infection of the middle ear. Otitis media is very common in young children. In a study of 168 same-sex twins and 7 triplets, the identical twins were much more likely to have the same number of infections that lasted a similar length of time as the fraternal twins. This may be due to anatomy, since studies have shown that a short, relatively straight eustachian tube is more prone to infection. Immunological factors may also be responsible.

Author: Rockette, Howard E., Kurs-Lasky, Marcia, Ferrell, Robert E., Bluestone, Charles D., Casselbrant, Margaretha L., Mandel, Ellen M., Fall, Patricia A.
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1999
Health aspects, Genetic aspects, Twins

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Effectiveness of inactivated influenza vaccine in preventing acute otitis media in young children: a randomized controlled trial

Article Abstract:

Influenza vaccine does not appear to reduce the risk of ear infections in young children, according to a study of 786 children between the ages of six months and two years. Although 90% of the vaccinated children created antibodies against the influenza virus, this did not protect them from ear infections or reduce their use of health care services.

Author: Paradise, Jack L., Colborn, D. Kathleen, Bernard, Beverly S., Rockette, Howard E., Kurs-Lasky, Marcia, Greenberg, David P., Lave, Judith R., Hoberman, Alejandro, Kearney, Diana H., Haralam, Mary Ann, Byers, Carol J., Zoffel, Lisa M., Fabian, Irene A., Kerr, Jill D.
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2003
Evaluation, Prevention, Influenza vaccines

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Subjects list: Otitis media
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