Deep-brain stimulation of the subthalamic nucleus or the pars interna of the globus pallidus in Parkinson's disease

Article Abstract:

Deep brain stimulation using implanted electrodes can inhibit the involuntary movement disorders in patients with Parkinson's disease, according to a study of 134 patients. The electrodes can inhibit specific areas of the brain without destroying brain tissue.

Movement disorders

---

Bilateral deep-brain stimulation of the globus pallidus in primary generalized dystonia

Article Abstract:

A prospective, controlled, multicenter study is conducted to assess the efficacy and safety of bilateral pallidal stimulation in 22 patients with primary generalized dystonia. The results reveal that the general health and physical functioning improved and there are no significant changes in measures of mood and cognition.

United Kingdom, Brain diseases, Dystonia

---

Electrical stimulation of the subthalamic nucleus in advanced Parkinson's disease

Article Abstract:

Electrical stimulation of a brain area called the subthalamic nucleus appears to be beneficial in patients with advanced Parkinson's disease. Many Parkinson's patients experience "off" periods when they do not respond to levodopa, the major drug used to treat the disease. Researchers implanted electrodes into the subthalamic nucleus in 24 Parkinson's patients. The electrodes were attached to an electrical generator that was placed under the skin like a heart pacemaker. After one year of stimulation, the dose of levodopa could be reduced and symptoms were less severe.

Similar abstracts:

• Abstracts: A comparison of methotrexate with placebo for the maintenance of remission in Crohn's disease. Treatment of ulcerative colitis with a humanized antibody to the alpha4beta7 integrin
• Abstracts: Long-term follow-up of unilateral pallidotomy in advanced Parkinson's disease. Posteroventral medial pallidotomy in advanced Parkinson's disease
• Abstracts: Identification of the Ebola virus glycoprotein as the main viral determinant of vascular cell cytotoxicity and injury
• Abstracts: Missense mutations in the rod domain of the lamin A/C gene as causes of dilated cardiomyopathy and conduction-system disease
• Abstracts: Depletion of host Langerhans cells before transplantation of donor alloreactive T cells prevents skin graft-versus-host disease

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.