Risk factors for severe hepatic injury after introduction of highly active antiretroviral therapy

Article Abstract:

About 10% of HIV patients who take highly active antiretroviral therapy (HAART) will develop liver damage from the drugs, according to a study of 222 HIV patients. The highest risk occurs in those with co-existing hepatitis C, those who use alcohol, and older patients.

HIV infection, HIV infections, Liver, Anti-HIV agents

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Early monitoring of ribavirin plasma concentrations may predict anemia and early virologic response in HIV/hepatitis C virus-coinfected patients

Article Abstract:

A study is carried out to assess whether the early monitoring of ribavirin(RBV) plasma levels could help to predict anemia as well as early hepatitis C virus (HCV) RNA response in HIV/HCV-coinfected individuals. It is found that the RBV levels correlate with the development of anemia and with the achievement of an early virologic response.

Science & research, Research, Anemia, Ribavirin, Hepatitis C virus

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Severe liver disease associated with prolonged exposure to antiretroviral drugs

Article Abstract:

Cryptogenic liver disease (CLD) is defined as persistently elevated aminotransferases levels in the absence of Hepatitis C and/or B viruses replication and of other common causes of liver disease. An analysis concluded that CLD is an uncommon condition in HIV-positive individuals and might be associated with prolonged didanosine.

United States, Health aspects, Causes of, Liver diseases, HIV patients, Antiviral agents, Antiretroviral agents, Clinical report

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