Effectiveness of combination antiretroviral therapy on survival and opportunistic infections in a developing world setting

Article Abstract:

An observational cohort study is used to describe the clinical response to antiretroviral therapy (ART), including long-term survival, among persons with HIV-1 who were enrolled and followed at the hospital. The analysis has showed the long-term effectiveness of ART in a developing country urban setting and has also shown the importance of continuing global financing initiatives to provide widespread HIV therapy for countries in the developing world.

Government domestic functions, Developing Countries, Evaluation, Patient outcomes, Highly active antiretroviral therapy, Urban health, Health policy, Clinical report

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High proportion of T-Cell systemic Non-Hodgkin lymphoma in HIV-infected patients in Lima, Peru

Article Abstract:

A report that describes the clinical and pathological characteristics of HIV-related systemic non-Hodgkin lymphoma (sNHL) in developing countries like Lima and Peru is presented. A high proportion of T-cell sNHL cases were found at an HIV reference-center in Peru, though B-cell and T-cell lymphoma patients had similar clinical characteristics, T-cell lymphoma was less aggressive and had a better survival rate than those of B-cell lymphoma.

Genetic aspects, Non-Hodgkin's lymphomas, Genetic research

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Enhanced replicative capacity and photogenicity of HIV-1 isolated from individuals infected with drug-resistant virus and declining CD4(super +) T-cell counts

Article Abstract:

A study was conducted to identify virologic correlates of enhanced CD4(super +) T-cell photogenicity in the setting of drug resistance. It was achieved by characterizing virus from discordant responders and nonresponders and evaluated replication capacity in thymus tissue and activated peripheral blood mononuclear cells (PBMCs) together with coreceptor usage.

Disease/Disorder overview

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