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Endothelial cells and VEGF in vascular development

Article Abstract:

Embryonic phenotypes that fail to develop different phases of the normal vasculature are reported for the vascular endothelial growth factor VEGF/VEGFR. Endothelial cells might probably have more interesting roles than just acting as channels for blood circulation and they can promote stem cell development and organ formation by acting as sources of paracrine signals to surrounding cells, both in development and in ongoing endothelial niches in the adult, both the process have serious implications.

Author: Rossant, Janet, Coultas, Leigh, Chawengsaksophak, Kallayanee
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2006
Phenotype, Phenotypes

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Annexin-V imaging for noninvasive detection of cardiac allograft rejection

Article Abstract:

Research has been conducted on the heart transplant rejection cause by myocyte necrosis and interstitial mononuclear cell filtration apoptosis. The clinical feasibility and safety of annexin-V imaging for the transplant rejection detection have been investigated via cell membrane phospholipid alteration targeting and the results are presented.

Author: Green, Allan, Narula, Jagat, Acio, Elmo R., Narula, Navneet, Samuels, Louis E., Fyfe, Billy, Wood, Diana, Fitzpatrick, Jane M., Raghunath, P. N., Tomaszewski, John E., Kelly, Christine, Steinmetz, Neil, Jain, Diwakar, Strauss, H. William, Blankenberg, Francis G., Leppo, Jeffrey, Tait, John F.
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2001
Genetic aspects, Cell death, Heart, Cell membranes, Phospholipids, Heart transplantation

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Molecular imaging of VEGF receptors in angiogenic vasculature with single-chain VEGF-based probes

Article Abstract:

This article describes the role played by vascular endothelial growth factor (VEGF) which are cell surface receptors and help in the vasculature of tumors. The experiment conducted is based on a single-chain of VEGF and is found to be useful for diagnosis, therapeutic monitoring and treatments.

Author: Blankenberg, Francis G., Backer, Marina V., Patel, Vimalkumar, Levashova, Zoya, Jehning, Brian T., Claffey, Kevin, Backer, Joseph M.
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2007
Usage, Cell surface antigens, Diagnostic imaging

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Subjects list: Health aspects, Research, United States, Vascular endothelial growth factor
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