Estrogen plus progestin and the risk of coronary heart disease

Article Abstract:

Hormone replacement therapy (HRT) should not be prescribed for healthy postmenopausal women to reduce their risk of developing coronary heart disease, according to the final results of the Women's Health Initiative study. This study of 16,608 postmenopausal women found that HRT actually increased their risk of developing coronary heart disease, particularly during the first year of use. The study was even stopped early because of this increased risk among HRT users.

Complications and side effects, Hormone therapy, Hormone replacement therapy

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Inflammatory markers and the risk of coronary heart disease in men and women

Article Abstract:

Plasma levels of soluble tumor necrosis factor receptors sTNF-R1 and sTNF-R2, interleukin-6, and C-reactive protein as markers of risk for coronary heart disease among women participating in the Nurses' Health Study and men participating in the Health Professionals Follow-up Study in nested case-control analyses are examined. Elevated levels of inflammatory markers, particularly C-reactive protein, indicate an increased risk of coronary heart disease.

United Kingdom, Science & research, Care and treatment, Research, C-reactive protein, Tumor necrosis factor, Tumour necrosis factor

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Estrogen therapy and coronary-artery calcification

Article Abstract:

A random clinical study aimed to ascertain the relation between estrogen therapy and calcification in the coronary artery, and the results are documented.

Pharmaceutical Preparation Manufacturing, Pharmaceutical preparations, Estrogen & Progestogen Preps, Health aspects, Patient outcomes, Estrogen, Estrogens, Calcification, Clinical report

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