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Estrogen receptor 1 variants and coronary artery disease: shedding light into a murky pool

Article Abstract:

A report published in 2003 provides more data on the role that estrogen plays in cardiovascular disease. The study found that men with a particular mutation in the gene for the estrogen receptor were more likely to have a heart attack. Genetic variations within populations may explain why estrogen seems to have contradictory effects. Some studies show it protects against heart disease while other studies show it increases the risk of heart disease.

Author: Brinton, Eliot A., Hopkins, Paul N.
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2003
Editorial, Risk factors, Genetic aspects, Heart attack, Estrogen, Estrogen receptors

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Peripheral Arterial Disease Detection, Awareness and Treatment in Primary Care

Article Abstract:

Many people have peripheral arterial disease and are not receiving appropriate treatment from their primary care physicians. Peripheral arterial disease is caused by the same process that causes coronary artery disease, and has many of the same risk factors. In a study of 6,979 patients, 29% had peripheral arterial disease.

Author: Hunninghake, Donald B., Olin, Jeffrey W., Hiatt, William R., Hirsch, Alan T., Criqui, Michael H., Treat-Jacobson, Diane, Regensteiner, Judith G., Creager, Mark A., Krook, Susan H., Comerota, Anthony J., Walsh, M. Eileen, McDermott, Mary M.
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2001
Peripheral vascular diseases

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Effect of Niacin on Lipid and Lipoprotein Levels and Glycemic Control in Patients With Diabetes and Peripheral Arterial Disease: The ADMIT Study

Article Abstract:

Niacin can increase blood levels of HDL, or 'good' cholesterol and lower blood levels of LDL, or 'bad' cholesterol in diabetics. Doctors should consider giving niacin to all diabetics with high cholesterol levels who cannot use other cholesterol-lowering drugs. Niacin is one of the B vitamins.

Author: Sheps, David S., Elam, Marshall B., Hunninghake, Donald B., Davis, Kathryn B., Garg, Rekha, Johnson, Craig, Egan, Debra, Kostis, John B., Brinton, Eliot A.
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2000
Physiological aspects, Diabetics, Hypercholesterolemia, Niacin

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Subjects list: Care and treatment
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