European Union research policy and funding for Alzheimer disease

Article Abstract:

Resources made available through research programs of the European Union (EU) on Alzheimer disease have doubled in Framework Program 6 (FP6) considering the challenges ahead and the necessity to support research on neurodegenerative diseases in general and Alzheimer's in particular. The approximate total funding of euro 40million and euro 20million for fiscal 2006 and 2005 respectively, is spread over 4 years each, and this represents only 5% of the total amount of public money spent on research in Europe.

Europe, Government domestic functions, Science and technology policy, European Union, Federal aid to research, Government aid to research

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Neuropathology of human alzheimer disease after immunization with amyloid-beta peptide: a case report

Article Abstract:

This article repots on immunotherapy of a 72-year old Alzheimer disease patient with amyloid-beta peptide. Results show extensive areas neocortex with very few amyloid-beta peptide whose immunoreactivity is associated with microglia. Data indicate that mice also show similar changes with the excepton of the presence of T-lymphocytemeningoencephalitis and macrophages infiltration of the cerebral white matter in the patient.

United Kingdom, Physiological aspects, Comparative analysis, Amyloid beta-protein, Immune response, Immunization

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Advances in the early detection of Alzheimer's disease

Article Abstract:

The progress in understanding of the evolution of early Alzheimer's disease (AD) is reviewed. Particular reference is given to the symptomatic pre-dementia stage designated 'mild cognitive impairment' emphasizing work on the early cognitive profile and associated neuroimaging studies.

Neurodegenerative diseases

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