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Flow cytometric analysis of lymph node metastases in advanced ovarian cancer: clinical and biologic significance

Article Abstract:

Lymph node metastases in cases of advanced ovarian cancer may contain cancer cells that are especially resistant to chemotherapy and radiation therapy. Researchers compared DNA content and S-phrase fraction in samples taken from the primary ovarian tumor, metastases elsewhere in the pelvic cavity, and metastases to pelvic and aortic lymph nodes in 35 women with stage III or stage IV ovarian cancer. Pelvic metastases had a similar profile to the primary tumor, but lymph node metastases were more likely to have characteristics known to be associated with resistance to treatment.

Author: Spirtos, Nick M., Schlaerth, John B., Ballon, Samuel C., Kute, Timothy E., Schlaerth, Alan C., Kimball, Ronald E., Santoso, Joseph
Publisher: Elsevier B.V.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 1997
Usage, Measurement, Genetic aspects, Flow cytometry, Cancer metastasis, Ploidy, Lymphatic metastasis

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Cost and quality-of-life analysis of surgery for early endometrial cancer: laparotomy versus laparoscopy

Article Abstract:

Early uterine cancer may be treated with laparoscopic surgery, resulting in shorter hospital stays, earlier recuperation, and lower costs. Researchers compared the outcomes of 17 women with early-stage endometrial cancer who underwent conventional abdominal surgery to the outcomes of 13 women with early endometrial cancer who underwent less invasive laparoscopy. Laparoscopy was limited to nonobese women. Hospital stays were three days shorter in the laparoscopy group, and less pain medication was used after laparoscopy. Both of these reductions translated to reduced costs.

Author: Spirtos, Nick M., Schlaerth, John B., Ballon, Samuel C., Gross, Gary M., Schlaerth, Alan C., Spirtos, Tanya W.
Publisher: Elsevier B.V.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 1996
Evaluation, Endometrial cancer, Laparoscopic surgery

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Second-look laparotomy after modified posterior exenteration: patterns of persistence and recurrence in patients with stage III and stage IV ovarian cancer

Article Abstract:

Pelvic exenteration appears to be effective in treating ovarian cancer that has spread to other abdominal organs. This technique involves removing as much cancerous abdominal tissue as possible. In a study of 151 women who had this procedure, only 5% had persistent abdominal cancer during a 12-month follow-up.

Author: Spirtos, Nick M., Eisenkop, Scott M., Schlaerth, John B., Ballon, Samuel C.
Publisher: Elsevier B.V.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 2000
Pelvis

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Subjects list: Ovarian cancer, Surgery
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