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Gastrointestinal Symptoms in 3181 Volunteers Ingesting Snack Foods Containing Olestra or Triglycerides

Article Abstract:

Consumption of snack chips cooked in olestra does not appear to cause significant gastrointestinal disturbances. Olestra is an undigestible cooking oil in which foods can be fried without adding dietary fat. Researchers supplied 3,181 people with packages of potato chips and corn chips fried in either olestra, or vegetable oil. About 37% of people in both groups reported one or more gastrointestinal symptoms, such as frequent bowel movements. Nausea was reported slightly more frequently by people eating regular snack chips, and increased bowel movements were reported slightly more often by those eating olestra-cooked chips.

Author: Sandler, Robert S., Zorich, Nora L., Filloon, Thomas G., Wiseman, Heather B., Lietz, Dennis J., Brock, Michael H., Royer, Mary G., Miday, Robert K.
Publisher: American College of Physicians
Publication Name: Annals of Internal Medicine
Subject: Health
ISSN: 0003-4819
Year: 1999
Edible fats and oils, Olestra, Oils and fats, Edible

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Breast Symptoms among Women Enrolled in a Health Maintenance Organization: Frequency, Evaluation, and Outcome

Article Abstract:

Women who visit the doctor with breast-related symptoms are very likely to require additional evaluations, diagnostic procedures, or treatment. Researchers investigated the frequency of breast symptoms during doctor visits by 2,400 women enrolled in a health maintenance organization insurance plan. In 10 years, 16% of the women sought care for breast-related symptoms. Two-thirds required additional medical evaluation beyond the initial visit. Invasive procedures, such as breast biopsy, were required in 27% of patients with breast symptoms, and 6% were diagnosed with breast cancer.

Author: Barton, Mary B., Fletcher, Suzanne W., Elmore, Joann G.
Publisher: American College of Physicians
Publication Name: Annals of Internal Medicine
Subject: Health
ISSN: 0003-4819
Year: 1999
Care and treatment, Diagnosis, Women, Breast cancer, Breast diseases

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The Role of Leptin in Human Obesity and Disease: A Review of Current Evidence

Article Abstract:

Leptin alters neuroendocrine function and influences the intake and expenditure of energy in the body. The hormone is secreted by fat cells in responses to changes in energy availability. In a review of 1,320 journal articles about leptin, a researcher describes leptin as a hormone may have an important role in the control of eating behavior and the development of obesity. Additional research may identify ways to use leptin or a similar substance to treat obesity and other eating disorders.

Author: Mantzoros, Christos S.
Publisher: American College of Physicians
Publication Name: Annals of Internal Medicine
Subject: Health
ISSN: 0003-4819
Year: 1999
Obesity, Leptin, Fat cells, Adipocytes

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Subjects list: United States, Physiological aspects
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