Histologic inflammation in the maternal and fetal compartments in a rabbit model of acute intra-amniotic infection

Article Abstract:

Infection in the uterus causes inflammation in the uterus, placenta, and fetal lung but not in other fetal organs. This was the conclusion of a study of pregnant rabbits. Inflammation of the uterus and placenta occurred before inflammation in the lung and the fetal brain was never affected.

Infection, Fetal membranes, Uterus

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Experimental intrauterine infection with prevotella bivia in New Zealand White rabbits

Article Abstract:

A study was undertaken to develop a model of chronic intrauterine and fetal infection with prevottela bivia, an anaerobe of the lower genital tract that is associated often with bacterial vaginosis. The result indicates that thirty timed pregnant New Zealand White rabbits were inoculated with P bivia solution, this model serve to explore the mechanism of preterm birth that is induced by chronic infection with genital tract anaerobes.

United States, New Zealand, Risk factors, Surveys, Vaginosis, Premature birth, Fetal diseases, Bacterial vaginosis

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A randomized trial of conjugated group B streptococcal type Ia vaccine in a rabbit model of ascending infection

Article Abstract:

A vaccine against group B streptococci that is linked to tetanus toxoid appears to be more effective than other vaccines in preventing serious infection in newborn babies. In a study of pregnant rabbits, the vaccine did not completely prevent the bacteria from being passed from mother to baby but did reduce the severity of the illness.

Evaluation, Streptococcal infections, Prevention, Bacterial vaccines

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