Hormone replacement therapy, hormone levels, and lipoprotein cholesterol concentrations in elderly women

Article Abstract:

Use of estrogen replacement therapy by postmenopausal women may lower blood levels of harmful cholesterol and raise blood levels of good cholesterol. Researchers analyzed the cholesterol levels of 84 postmenopausal women taking estrogen replacement therapy, and of 38 postmenopausal women taking a combination hormone replacement therapy. Blood levels of women taking estrogen replacement therapy and women taking combination hormone replacement therapy showed decreases of low density lipoprotein (LDL) cholesterol, a harmful cholesterol, and increases of high density lipoprotein (HDL) cholesterol, which is beneficial. Combination therapies include both estrogen and progestin. Doctors may need to monitor cholesterol levels in patients taking estrogen replacement therapies.

Blood cholesterol

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Effects of adding C-19 versus C-21 progestin to conjugated estrogen in moderately hypercholesterolemic postmenopausal women

Article Abstract:

Both norgestrel and medroxyprogesterone raise the level of high-density-lipoprotein (HDL) cholesterol. High blood levels of HDL, or 'good' cholesterol can lower the risk of heart disease. Researchers gave 9 women with elevated blood cholesterol levels hormone therapy with estrogen plus norgestrel or medroxyprogesterone. Progesterone and its derivatives are often used in hormone therapy to eliminate the adverse effects of estrogen. Both progesterone hormones raised blood levels of HDL cholesterol and lowered total cholesterol levels.

Cholesterol, HDL, HDL cholesterol lipoproteins, Progestational hormones

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Female sexual dysfunction in postmenopausal women: systematic review of placebo-controlled trials

Article Abstract:

Many treatments for female sexual disorders in postmenopausal women have not been properly evaluated. Only six clinical trials have been done: one testing Viagra, three testing hormone replacement therapy (HRT), and two testing tibolone. Tibolone and HRT may be beneficial, although androgen therapy may have serious side effects.

Sexual disorders, Drug therapy

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