Immunotherapy with a ragweed-toll-like receptor 9 agonist vaccine for allergic rhinitis

Article Abstract:

A small, placebo-controlled clinical trial in which patients who were allergic to ragweed were immunized with a six-injection regimen of the AIC vaccine before the first ragweed season and evaluated during the next two ragweed seasons. The study provides preliminary evidence that a six-injection regimen of AIC reduces allergic rhinitis symptoms during the ragweed season and the clinical effects of AIC appear to be associated with the induction of long-lasting immune modulation.

Health aspects, Usage, Hay-fever, Immunotherapy, Allergic rhinitis, Ragweeds

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Safety and efficacy of a recombinant hepatitis E vaccine

Article Abstract:

The safety and efficacy of a hepatitis E virus (HEV) recombinant protein (rHEV) vaccine was evaluated in a phase 2, randomized, double-blind, placebo-controlled trial. Results suggested that in a high-risk population, the rHEV vaccine was effective in the prevention of hepatitis E.

Hepatitis, Viral, Viral hepatitis, Hepatitis E virus

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The liver X receptor and atheroscelerosis

Article Abstract:

The research work related to liver X receptor (LXR)[beta]-specific agonist ligands is reviewed. LXR[beta] could be targeted for the treatment of atherosclerosis, which is the major cause of cardiovascular disease.

Cardiovascular diseases, Atherosclerosis

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