Detection of prions in blood

Article Abstract:

A demonstration that the protein misfolding cyclic amplification (PMCA) technology could be automated and optimized for high-efficiency amplification of prion protein (PrP(super Sc)) is presented. Notably, serial PMCA enables detection of PrP(super Sc) in blood samples of scrapie-afflicted hamsters with 89% sensitivity and 100% specificity.

Prions, Prions (Proteins), Protein folding

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Oxidative stress is the new stress

Article Abstract:

A new study in the genetics of anxiety shows that two enzymes, glyoxalase 1 and glutathione reductase 1, are highly correlated with anxiety levels. These enzymes modulate the levels of oxidative stress, which is caused by the production of free oxygen radicals.

Health aspects, Genetic aspects, Anxiety, Oxidative stress

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