Import of host delta-aminolevulinate dehydratase into the malaraial parasite: identification of a new drug target

Article Abstract:

Research reveals that a 93-amino acid fragment of the human erythrocyte delta-aminolevulinate dehydratase enzyme inhibits the enzyme synthesis, activity, and heme synthesis in Plasmodium berghei in the infected red blood cells. Data indicate that a 65 kilodalton protein on the the parasite binds the protein fragment involved in the inhibition.

Physiological aspects, Enzymes, Proteins, Protein structure, Enzyme structure-activity relationships, Heme, Enzyme inhibitors

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Fishy asthma cure raises big stink in India

Article Abstract:

The treatment for asthma, by swallowing a two-inch fish stuffed with unknown an herbal composition, which is held in Hyderabad every Mrigasira Karti an auspicious day on Hindu calendar is illustrated. There are researches made for endorsing this controversial unlawful and unethical treatment.

Commercial Fishing, Fishing, Edible Fish, Usage, Evaluation, Asthma, Fish as food, Fish (Food product)

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Triclosan offers protection against blood stages of malaria by inhibiting enoyl-ACP reductase of 'Plasmodium falciparum'

Article Abstract:

The enoyl-ACP reductase extracted from Plasmodium falciparum, responsible for malaria, has been shown to be sensitive to triclosan. Triclosan, a common antimicrobial biocide, could offer a pathway to development antimalarial treatment.

Health aspects, Anti-infective agents

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