A B-cell mitogen from a pathogenic trypanosome is a eukaryotic proline racemase

Article Abstract:

Research examines the role of polyclonal activation in the mechanism of infection resistance and immune responses in Trypanosoma cruzi infection. Results show that a proline racemase expressed as a cytoplasmic and/or membrane-asociated protein is involved in the mitogenic activity.

Portugal, Brazil, Analysis, Infection, Lymphocyte transformation, B cells, Cell differentiation, Immune response, Trypanosoma cruzi

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Kourilsky to reform the Pasteur Institute

Article Abstract:

Philippe Kourilsky became the director of the Pasteur Institute in Jan 2000. Kourilsky has begun a 4-year review for directors, is creating small laboratories staffed by young researchers, and will divert 30% of lab funds into a common pool for inter-laboratory projects.

Officials and employees, Appointments, resignations and dismissals, Medical research, Kourilsky, Philippe, Pasteur Institute

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MEK wars, a new front in the battle against cancer

Article Abstract:

A new front exists front in the battle against cancer and the new P184352 is there to help in the fight. A specific inhibitor of the mitogen-activated protein kinase (MAPK or ERK) pathway is a new member in the search for cytostatic drugs that block tumor growth

United States, Research, Cancer research, Cancer, Protein kinases

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