Intra-articular corticosteroid injections in osteoarthritis: do they work and if so, how?
Article Abstract:
Using magnetic resonance imaging or measuring changes in the serum or joint fluid to identify inflammatory episodes in patients with osteoarthritis could facilitate research on treatment with intra-articular (IA) corticosteroid injections. Controlled studies of steroid injections in the joints of people with osteoarthritis fail to explain marked differences in pain relief observed between patients. Corticosteroids interrupt inflammatory reactions. Inflammation differs among subgroups of osteoarthritis and appears to occur in phases. Identification of inflammatory episodes would allow treatment of those most likely to benefit and provide information on the mechanism of the action of IA corticosteroids.
Publication Name: Annals of the Rheumatic Diseases
Subject: Health
ISSN: 0003-4967
Year: 1997
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Polyarthritis and pitting oedema
Article Abstract:
Doctors describe three patients who characterize the symptoms and treatment of polyarthritis with pitting edema. Each patient developed joint pain in the hands, with swelling that formed pits when pressure was applied to the fluid-swollen hand. Laboratory signs include an elevated red blood cell sedimentation rate, inflammatory anemia, and no antinuclear antibodies. The symptoms mimic rheumatoid arthritis, connective tissue diseases, psoriatic arthritis, and other conditions. Prompt treatment with corticosteroids often produces rapid and persistent relief.
Publication Name: Annals of the Rheumatic Diseases
Subject: Health
ISSN: 0003-4967
Year: 1999
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Use of an objective measure of articular stiffness to record changes in finger joints after intra-articular injection of corticosteroid
Article Abstract:
There appear to be some useful and measurable differences in joint condition among patients treated by injections for arthritis in their fingers. Pressure and computer driven devices were used to measure range of motion, stiffness, and pain levels among 15 patients with arthritis before, one day after, and one week after injections into their finger joints. After one week there was measurable improvement in all criteria after an initial but insignificant increase in joint stiffness.
Publication Name: Annals of the Rheumatic Diseases
Subject: Health
ISSN: 0003-4967
Year: 1997
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