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Laboratory test differences associated with HTLV-I and HTLV-II infection

Article Abstract:

Infection with human T-cell leukemia viruses (HTLV) may cause an increase in the lymphocyte count and changes on blood tests. HTLV causes adult T-cell leukemia, autoimmune conditions, and a neurologic syndrome. Researchers performed blood tests on 539 blood donors with HTLV infection and 795 HTLV-negative blood donors. Absolute lymphocyte counts were 6% higher in HTLV-I-positive donors and 10% higher in HTLV-II-positive donors. HTLV-infected donors had more platelets in the blood, and HTLV-II-infected donors had lower calcium and creatine kinase levels in their blood.

Author: Murphy, Edward L., Wright, David, Schreiber, George, Smith, James, Sacher, Ronald, Luban, Naomi, Watanabe, Kevin, Glynn, Simone, Fridey, Joy
Publisher: Lippincott Williams & Wilkins, WK Health
Publication Name: Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology
Subject: Health
ISSN: 1077-9450
Year: 1998
Measurement, Creatine kinase, HTLV-II infections, Lymphocytes

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Altered cell-mediated immunity in asymptomatic Colombian natives with positive or indeterminate serology for HTLV-I

Article Abstract:

The immune response appears to be altered in people with HTLV-I infection even if they have no symptoms. Researchers tested cell-mediated immunity in 40 HTLV-I-infected asymptomatic Colombian Indians and 30 healthy Indians with skin testing using seven different antigens. HTLV-I-infected Indians had fewer positive reactions than the healthy Indians.

Author: Bernal, Carlos, Bernal, Ernesto, Patarca, Roberto, Bonilla, Ruben Dario, Arango, Cesar
Publisher: Lippincott Williams & Wilkins, WK Health
Publication Name: Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology
Subject: Health
ISSN: 1077-9450
Year: 1998
Testing, Cellular immunity

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Subjects list: Physiological aspects, HTLV-I infections
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