Lenalidomide in the myelodysplastic syndrome with chromosome 5q deletion

Article Abstract:

A multicenter international study was carried out to determine the frequency of erythroid and cytogenetic responses to lenalidomide therapy in transfusion-dependent patients with the myelodysplastic syndrome and the 5q31 deletion. The findings suggest that lenalidomide could reduce transfusion requirements and reverse cytologic and cytogenetic abnormalities in patients who have the myelodysplastic syndrome with the 5q31 deletion.

Care and treatment, Genetic aspects

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Efficacy of lenalidomide in myelodysplastic syndromes

Article Abstract:

The safety and hematologic activity of lenalidomide, a novel analogue of thalidomide, is evaluated in patients with myelodysplastic syndromes and symptomatic anemia. Lenalidomide has hematologic activity in patients with low-risk myelodysplastic syndromes who have no response to erythropoietin or who are unlikely to benefit from conventional therapy.

United Kingdom, Anemia, Thalidomide

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Lenalidomide plus dexamethasone for relapsed multiple myeloma in North America

Article Abstract:

The efficacy of lenalidomide plus dexamethasone with placebo plus dexamethasone to treat multiple myeloma was determined among patients in the United States and Canada. lenalidomide plus dexamethanose was found to be more competent than placebo plus dexamethanose.

Canada, Health aspects, Comparative analysis, Drug therapy, Combination, Combination drug therapy, Dexamethasone, Multiple myeloma, Clinical report

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