Lipoprotein receptor-mediated induction of matrix metalloproteinase by tissue plasminogen activator

Article Abstract:

Research shows that tissue plasminogen activator is involved in the upregulation of matrix metalloproteinase-9 both in vivo and in vitro. Results reveal that the matrix metalloproteinase-9 upregulation in human cerebral microvascular endothelial cells upon tissue plasminogen activator addition is mediated by the low-density lipoprotein receptor-related protein, which binds tissue plasminogen activator.

Cellular control mechanisms, Cell regulation, Low density lipoproteins, Metalloenzymes, Tissue plasminogen activator, Enzyme activation

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Alternatively spliced human tissue factor: a circulating, soluble, thrombogenic protein

Article Abstract:

Results reveal that the spliced human tissue factor exhibits much of the extracellular domain of the unspliced tissue factor but without a transmembrane domain. It circulates in blood, possesses pro-coagulant activity, and incorporated into thrombi.

Analysis, Proteins, Structure-activity relationships (Biochemistry), Thrombosis, Coagulation, Blood circulation, Structure, Blood clot

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Role of teichoic acids in Staphylococcus aureus nasal colonization, a major risk factor in nosocomial infections

Article Abstract:

Wall teichoic acid (WTA), a surface-exposed staphylococcus polymer, is essential for nasal colonization and mediates interaction with human nasal epithelial cells. The study describes the first essential factor for S.aureus nasal colonization.

Science & research, All Other Basic Organic Chemical Manufacturing, Industrial organic chemicals, not elsewhere classified, Antioxidants, Antioxidants & Antiozonants, Research, Risk factors, Staphylococcus aureus, Nosocomial infections, Cross infection, Polymer antioxidants (Additives)

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