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Magnetic resonance-guided, real-time targeted delivery and imaging of magnetocapsules immunoprotecting pancreatic islet cells

Article Abstract:

Magnetic resonance-trackable magnetocapsules are used simultaneously for immunoprotecting pancreatic [beta]-cells and for monitoring, non-invasively in real-time, hepatic delivery and engraftment by magnetic resonance imaging (MRI). The results are applicable to the improvements in islet cell transplantation for human diabetes.

Author: Stuber, Matthias, Bulte, Jeff W.M., Walczak, Piotr, Barnett, Brad P., Arepally, Aravind, Karmarkar, Parag V., Di Qian, Gilson, Wesley D., Howland, Valerie, Lawler, Leo, Lauzon, Cal, Kraitchman, Dara L.
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2007
Care and treatment, Diabetes, Diabetes mellitus, Pancreatic beta cells, Clinical report

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In vivo magnetic resonance imaging of acute brain inflammation using microparticles of iron oxide

Article Abstract:

A magnetic resonance imaging model which detects vascular cell adhesion molecule-1 (VCAM-1) expression in vivo in mouse brain inflammation is reported. The technology could be applied to monitor expression of endovascular molecules in vivo in various pathologies.

Author: Schneider, Jurgen E., Anthony, Daniel C., McAteer, Martina A., Sibson, Nicola R., Muhlen, Constantin von zur, Lowe, Andrew S., Warrick, Nicholas, Channon, Keith M., Choudhury, Robin P.
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2007
Cell adhesion, Ferric oxide

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Telomere dysfunction induces environmental alterations limiting hematopoietic stem cell function and engraftment

Article Abstract:

The study report on telomere dysfunction which induces alterations of the environment that could have implications for organisms aging and cell transplantation therapies is presented.

Author: Hong Jiang, Trumpp, Andreas, Rathinam, Chozhavendan, Klein, Christoph, Zhenyu Ju, Maike Jaworski, Gompf, Anne, Rudolph, Lenhard K.
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2007
Telomerase

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Subjects list: Health aspects, Research, Usage, Magnetic resonance imaging, Cells, Cell transplantation
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