Masoprocol for multiple actinic keratoses

Article Abstract:

Actinic keratoses, a skin disease resulting from chronic ultraviolet light exposure, can be treated with Actinex. Actinex is a topical cream containing 10% masoprocol. In a clinical trial of 113 patients, 50% percent of actinic keratoses patients who applied masoprocol twice daily for 14 to 28 days showed marked improvement and 11% were cured. The recommended treatment is twice daily application for 28 days. Adverse effects, leading to the exclusion of 25 patients in the trial, included erythema, a reddening or inflammation of the skin; itching, flaking, burning and soreness; edema; and allergic dermatitis. The longterm effects of the cream require further study. Actinex costs pharmacists $48 for 30 grams, which is slightly more expensive than the leading fluorouracil topical treatment. but causes less severe reactions.

Evaluation, Drug therapy, Actinex (Medication)

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Epinastine ophthalmic solution (ELESTAT)

Article Abstract:

Epinastine HCl an H (sub 1)-receptor antagonist and most cell stabilizer, has been approved by the FDA for use in a 0.05% ophthalmic solution for prevention of itching associated with allergic conjunctivitis. The most important thing is that contact lenses should be removed before and they can be reinserted ten minutes later.

Allergy, Allergic reaction, Ophthalmic solutions

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Imiquimod (Aldara) for actinic keratoses

Article Abstract:

The approval of imiquimod cream 5 percent (Aldara - 3M) by the FDA is discussed. The drug is useful for treating actinic keratoses (AKs) on the face or scalp and also acts on subclinical and clinically detectable lesions.

United States, Usage, Imiquimod

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