Measurement characteristics of anal cytology, histopathology, and high-resolution anoscopic visual impression in an anal dysplasia screening program

Article Abstract:

The estimated agreement between consecutive anal cytologic examinations, between concurrent cytologic examinations, histopathology, between highresolution anoscopy (HRA) visual impression and histopathology and the estimation of the prevalence of severe dysplasia by concurrent cytologic category is studied. The candidate interventions to treat or prevent precursor lesions from entering clinical development, standardization and improvement of measurement methods are essential.

Product standards, safety, & recalls, Standards, Methods, Analysis, Medical examination, Histology, Pathological, Pathological histology, Dysplasia, Physical diagnosis, Periodic health examinations, Anorectal disorders

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Depletion in antibodies targeted to the HR2 region of HIV-1 glycoprotein gp41 in sera of HIV-1-seropositive patients treated with T20

Article Abstract:

An investigation on the levels of antibodies directed to the gp160 molecule in patients treated with T20 by enzyme-linked immunosorbent is presented using plates coated with T20 or with synthetic peptides and recombinant proteins representing gp120 or gp41 domains. It concluded that the levels of antibodies directed to the HR2 region were decreased following treatment of HIV-1-infected patients with T20.

Care and treatment, HIV (Viruses), HIV, Protein binding, Viral antibodies, Antibodies

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