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Cannabinoid activity curtails cocain craving

Article Abstract:

Research has been conducted on the cocain relapse. The mechanism involved in the cocaine relapse has found to be connected to the sites affected by marijuana and the results indicate that the cannabinoid receptor antagonists may be used as anti-craving agents.

Author: Piomelli, Daniele
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2001
Marijuana

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A cannabinoid mechanism in relapse to cocaine seeking

Article Abstract:

Research has been conducted on the neuronal mechanisms underlying the relapse to cocaine. The results indicate that the synthetic cannabinoid agonist provokes the relapse to the cocaine seeking after the long withdrawal periods.

Author: Shaham, Yavin, Vries, Taco J. de, Homberg, Judith R., Crombag, Hans, Schuurman, Karianne, Dieben, Jeanine, Vanderschuren, Louk J. M. J., Schoffelmeer, Anton N. M.
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2001
Netherlands, Statistical Data Included, Neurons

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Modulation of anxiety through blockade of anandamide hydrolysis

Article Abstract:

Research suggests that anandamide modulates the emotional states and fatty acid amide hydrolase inhibition serves as anti-anxiety therapy. The isomer of anti-cholinesterase agent carbaryl inhibits the enzyme that is involved in the degradation of the cannabinoid anandamide thereby enhancing its level in the brain.

Author: Piomelli, Daniele, Kathuria, Satish, Gaetani, Silvana, Fegley, Darren, Valino, Fernando, Duranti, Andrea, Tontini, Andrea, Mor, Marco, Tarzia, Giorgio, Rana, Giovanna La, Calignano, Antonio, Giustino, Arcangela, Tattoli, Maria, Palmery, Maura, Cuomo, Vincenzo
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2003
Italy, Pharmaceutical Preparation Manufacturing, Pharmaceutical preparations, Enzyme Inhibitors, Drug therapy, Brain, Anxiety

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Subjects list: United States, Analysis, Physiological aspects, Medical research, Cannabinoids, Cocaine
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